Isoleucine is one of the nine indispensable amino acids that cannot be synthesized to meet body needs in animals and therefore must be provided in the diet.
The branched-chain amino acids (BCAA), including isoleucine (Ile), leucine, and valine, in addition to precursor function, also play important roles in control of energy homeostasis, nutritional metabolism, immunity, and intestinal health in animals.
As a functional branched amino acid, isoleucine (Ile) plays an outstanding role in promoting animal growth and development and protecting animal health.
Isoleucine may be the third or fourth limiting amino acid in the commercial diet, and the optimal Ile/Lys ratio might affect broiler production performance. Dietary Ile could improve growth performance and the digestibility of nutrients, and enhance intestinal health by modulating intestinal immunity, antioxidant capacity, tight junction proteins and microbial populations.
Dietary isoleucine supplementation enhances growth performance, modulates the expression of genes related to protein metabolism, and gut microbiota in yellow-feathered chickens.
What impact will lack of isoleucine in the diet have on livestock and poultry?
1. The lack of isoleucine in the feed will have a negative impact on the growth performance, carcass traits and muscle fat content of finishing pigs.
2. The lack of isoleucine in the feed will seriously affect the feed intake of breeders, resulting in weight loss and lower egg production performance.
3. The lack of isoleucine in the feed will reduce the blood sugar level of the cows and reduce the milk production of the cows.
Benefits of Iso – leucine amino diet for animals
Animals need sufficient amounts of all amino acids to meet their metabolic needs, whether they need to produce milk, build muscle and tissues or reproduce. Depending on what each animal needs, it may produce different proteins in varying amounts, which may require a different number of specific amino acids. Hence providing sufficient amounts of all essential amino acids in the diets of production animals is paramount.
Presence of iso – leucine in diet Improves meat quality, increase milk and egg production. Promote gluconeogenesis and enhance the immunity of animals.
The ratio of Ile to Lys as a method of balancing protein in the diet is to optimize protein utilization from the diet. Previous studies have shown that the optimal digestible Ile/Lys in commercial broilers was 0.71 so it was reported that dietary Ile could improve growth performance and the digestibility of nutrients, and enhance intestinal health by modulating intestinal immunity, antioxidant capacity, tight junction proteins and microbial populations.
As branched-chained amino acids (BCAAs), isoleucine is important for maintaining gut immunity, antioxidant capacity, and critical metabolic processes. Isoleucine is essential for growth, optimum egg mass, and egg production. BCAAs are thought to be important in egg production due to regulation of fatty acid metabolism in the liver where production of lipoprotein could be rate-limiting for egg yolk formation.
We at Afvet are into manufacturing and supply of all essential high end aminos and specialty feed supplements including Iso – leucine to more than 30 countries of the world. Some of the major countries where we are selling are Honduras, Guatemala, Ethiopia, Indonesia, Turkey, Philippines, Algeria, Romania, Venezuela, Nepal, Bangladesh, Dubai (UAE), Jordan etc.
